Genetic and Epigenetic Factors in Risk and Susceptibility for Childhood Asthma

Asthma is a common respiratory disease that affects people of all ages, characterized by considerable heterogeneity in age, clinical presentation, genetics, epigenetics, environmental factors, treatment response, and prognostic outcomes. more than 330 million worldwide, which 33% are children under 14 years, 27% adults whose first symptoms occurred childhood. However, the genetic epigenetic mechanisms childhood allergic diseases asthma still not fully understood. Here, we conducted biomedical narrative review genes associated with risk, severity, susceptibility since it differs from regarding their pathophysiology, development, We also systematized available information on changes asthma.